Specialty
Certifications
Neurology, American Board of Psychiatry and Neurology
Clinical Focus
Education
MD, Jefferson Medical College
Residency, Internal Medicine
Bronx Municipal Hospital CenterResidency, Neurology
New York Hospital
Biography
- Fred D. Lublin, MD is the Saunders Family Professor of Neurology and the Director of the Corinne Goldsmith Dickinson Center for Multiple Sclerosis at Mount Sinai Medical Center. He is an internationally renowned authority on the clinical and scientific aspects of MS and one of the foremost experts in experimental therapies.
As a neuroimmunologist, Dr. Lublin has a special interest in immune functions and abnormalities affecting the nervous system. He has been involved in both basic science and clinical research. In 2005, Dr. Lublin received a $25-million grant from the National Institutes of Health (NIH) to conduct a nationwide multi-center study on the effectiveness of combining two disease-modifying drugs. This grant was renewed in 2008, bringing the total allocated by the NIH to $44-million, one of the largest grants ever given for MS research.
Learn more about Dr. Lublin's work as Principal Investigator in the CombiRx clinical trial, as this study is known, in Inside Mount Sinai. He is also currently involved in several new clinical research protocols on promising agents for treating various aspects of MS.
Dr. Lublin was chairman of the National Multiple Sclerosis Society (USA) advisory committee on clinical trials of new MS drugs; and he is currently chair of the Clinical Advisory Committee of the New York City Chapter of the National MS Society. Dr. Lublin and his colleagues at the National MS Society (USA) have redefined the clinical course definitions of MS.
Dr. Lublin has published numerous scientific articles and belongs to many professional societies and advisory boards. Dr. Lublin has served as a consultant to the NIH, as well as to pharmaceutical and biotech companies in all phases of drug development, and in preparation for drug presentation to the FDA and its advisory panels.
Dr. Lublin received his medical degree at Jefferson Medical College, Philadelphia, PA. He completed his internship in Internal Medicine at the Bronx Municipal Hospital, Albert Einstein Medical Center, and his residency at the New York Hospital, Cornell Medical Center.
In the News
Dr. Lublin discusses multiple sclerosis in The Daily News feature The Daily Check Up.
View the PDF.
Awards
2001 -
Attending of the Year Award
Mount Sinai Medical Center Neurology Residents2000 - Present
Chairman, Research Programs Advisory Committee
National Multiple Sclerosis Society1999 -
McEwan Visiting Professorship & Lecture in Neurology
University of Toronto1999 -
Hope Award
National Multiple Sclerosis Society, Delaware Valley Chapter1996 -
Milestone Award
National Multiple Sclerosis Society, Delaware Valley Chapter
Publications
Miller A, Bourdette D, Cohen JA, Coyle PK, Lublin F, Paty DW, Rice GP, Weinstock-Guttman B, editors. Multiple Sclerosis. New York, Continuum; 1999. pp1-196.
Croul S, Lublin F, Del Valle L, Oshinsky RJ, Giordano A, Khalili K, Ritchie CK. The Cellular Response of JC Virus T-Antigen-Induced Brain Tumor Implants to a Murine Intra-Ocular Model. J Neuroimmunol 2000; 106: 181-188.
Wolinsky JS, Narayana PA, Noseworthy JH, Lublin F, Whitaker JN, Linde A, Gjorstrup P, Sullivan HC. Linomide in relapsing and secondary progressive MS: part II: MRI results. MRI Analysis Center of the University of Texas-Houston, Health Science Center, and the North American Linomide Investigators. Neurology 2000 May; 54(9): 1734-1741.
Noseworthy JH, Wolinsky JS, Lublin F, Whitaker JN, Linde A, Gjorstrup P, Sullivan HC. Linomide in relapsing and secondary progressive MS: part I: trial design and clinical results. North American Linomide Investigators. Neurology 2000 May; 54(9): 1726-1733.
Whitaker JN, Wolinsky JS, Narayana PA, Bartolucci AA, Noseworthy JH, Lublin F, Linde A, Gjorstrup P, Sullivan HC, North American Linomide Investigators . Relationship of urinary myelin basic protein-like material with cranial magnetic resonance imaging in advanced multiple sclerosis. Arch Neurol 2001 Jan; 58(1): 49-54.
Kalman B, Lublin F. Spectrum and classification of inflammatory demyelinating diseases of the central nervous system. Current Neurology and Neuroscience Reports, Demyelinating Disorders section 2001; 1: 249-256.
McDonald WI, Compston DA S, Edan G, Goodkin D, Hartung HP, Lublin F, McFarland HF, Paty D, Polman CH, Reingold SC, Sandberg-Wollheim M, Sibley W, Thompson A, van den Noort S, Weinshenker B, Wolinsky JS. Diagnostic Criteria for MS: Guidelines from the International Panel on the Diagnosis of MS. Ann Neurol 2001; 50: 121-127.
Lublin F, Reingold SC. Placebo-controlled clinical trials in multiple sclerosis: ethical considerations. National Multiple Sclerosis Society (USA) Task Force on Placebo-Controlled Clinical Trials in MS. Ann Neurol 2001; 49: 677-681.
Mohamed FB, Vinitski S, Gonzalez CF, Faro SH, Lublin F, Knobler R, Gutierrez JE. Increased differentiation of intracranial white matter lesions by multispectral 3D-tissue segmentation: preliminary results. Magn Reson Imaging 2001; 19: 207-18.
Clinical Trials
Industry Relationships
Physicians and scientists on the faculty of Mount Sinai School of Medicine often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Lublin during 2011 and/or 2012. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Consulting:
- Acorda Therapeutics Inc.; Actelion Pharmaceuticals Ltd.; Bayer; Biogen Idec; Bristol-Myers Squibb; Celgene Corporation; Coronado Biosciences; EMD Serono, Inc. (Merck & Co., Inc.); F. Hoffman-La Roche Ltd.; Genzyme Corporation; Johnson & Johnson Services, Inc.; Kyowa Hakko Kirin Pharma, Inc. (KKP); MedImmune, LLC; Novartis; Questcor Pharmaceuticals, Inc.; Revalesio Corporation; Teva Pharmaceutical Industries Ltd.; XenoPort, Inc.; sanofi-aventis
Scientific Advisory Board:
- Bayer; Pfizer Inc.
Industry-Sponsored Lectures: MSSM faculty occasionally give lectures at events sponsored by industry, but only if the events are free of any marketing purpose.
- Biogen Idec
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website at http://www.mssm.edu/about-us/services-and-resources/faculty-resources/handbooks-and-policies/faculty-handbook. Patients may wish to ask their physician about the activities they perform for companies.
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